Pirb - paired Ig-like receptor B

Predicted to enable amyloid-beta binding activity; inhibitory MHC class I receptor activity; and protein homodimerization activity. Predicted to be involved in several processes, including negative regulation of osteoclast differentiation; regulation of protein metabolic process; and regulation of synaptic plasticity. Predicted to act upstream of or within B cell homeostasis; B cell mediated immunity; and myeloid dendritic cell differentiation. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Orthologous to human LILRB3 (leukocyte immunoglobulin like receptor B3) and LILRB5 (leukocyte immunoglobulin like receptor B5). [provided by Alliance of Genome Resources, Apr 2022]