Isx - intestine-specific homeobox

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in enteric nervous system development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of intestinal absorption and regulation of vitamin A metabolic process. Predicted to be located in nucleus. Orthologous to human ISX (intestine specific homeobox). [provided by Alliance of Genome Resources, Apr 2022]