Cgas - cyclic GMP-AMP synthase

Predicted to enable several functions, including 2',3'-cyclic GMP-AMP synthase activity; chromatin binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including positive regulation of intracellular signal transduction; regulation of cellular response to stress; and regulation of defense response. Predicted to act upstream of or within several processes, including determination of adult lifespan; regulation of T cell activation; and regulation of gene expression. Predicted to be located in several cellular components, including cytosol; nucleus; and site of double-strand break. Orthologous to human CGAS (cyclic GMP-AMP synthase). [provided by Alliance of Genome Resources, Apr 2022]