Ndufc2 - NADH:ubiquinone oxidoreductase subunit C2

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in several processes, including mitochondrial respiratory chain complex I assembly; negative regulation of NIK/NF-kappaB signaling; and positive regulation of ATP biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including gut; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2). [provided by Alliance of Genome Resources, Apr 2022]