Arl13b - ADP-ribosylation factor-like 13B

Predicted to enable GTP binding activity. Involved in nervous system development; non-motile cilium assembly; and smoothened signaling pathway. Acts upstream of or within dorsal/ventral pattern formation; heart looping; and left/right axis specification. Located in axoneme; ciliary membrane; and motile cilium. Is expressed in several structures, including chordamesoderm; embryo mesenchyme; future spinal cord; lateral ventricle; and node. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Orthologous to human ARL13B (ADP ribosylation factor like GTPase 13B). [provided by Alliance of Genome Resources, Apr 2022]