Tdgf1 - teratocarcinoma-derived growth factor 1

Predicted to enable several functions, including Wnt-protein binding activity; nodal binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and circulatory system development. Predicted to act upstream of or within several processes, including circulatory system development; negative regulation of transforming growth factor beta receptor signaling pathway; and positive regulation of nitrogen compound metabolic process. Predicted to be located in several cellular components, including apical plasma membrane; membrane raft; and perinuclear region of cytoplasm. Predicted to be extrinsic component of plasma membrane. Predicted to be active in cell surface and extracellular region. Human ortholog(s) of this gene implicated in colon cancer and congenital heart disease. Orthologous to human TDGF1 (teratocarcinoma-derived growth factor 1). [provided by Alliance of Genome Resources, Apr 2022]