Pramex1 - PRAME like, X-linked 1

Predicted to enable retinoic acid receptor binding activity and ubiquitin ligase-substrate adaptor activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of retinoic acid receptor signaling pathway; and negative regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to be active in chromatin; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human PRAME (PRAME nuclear receptor transcriptional regulator). [provided by Alliance of Genome Resources, Apr 2022]