Pam16 - presequence translocase associated motor 16

Involved in negative regulation of apoptotic DNA fragmentation and negative regulation of release of cytochrome c from mitochondria. Predicted to be located in mitochondrial matrix. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be part of PAM complex, Tim23 associated import motor. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Megarbane-Dagher-Melike type. Orthologous to human PAM16 (presequence translocase associated motor 16). [provided by Alliance of Genome Resources, Apr 2022]