Ift74 - intraflagellar transport 74

Enables chromatin binding activity. Acts upstream of or within several processes, including keratinocyte development; non-motile cilium assembly; and positive regulation of cell adhesion mediated by integrin. Located in centrosome; cilium; and nucleus. Part of intraciliary transport particle B. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Used to study visceral heterotaxy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 22. Orthologous to human IFT74 (intraflagellar transport 74). [provided by Alliance of Genome Resources, Apr 2022]