Alkbh8 - alkB homolog 8, tRNA methyltransferase

Enables 2-oxoglutarate-dependent dioxygenase activity; catalytic activity, acting on a tRNA; and iron ion binding activity. Involved in tRNA methylation and tRNA wobble uridine modification. Predicted to be located in cytosol and nuclear body. Predicted to be active in cytoplasm and nucleus. Is expressed in nervous system and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human ALKBH8 (alkB homolog 8, tRNA methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]