Enables ubiquitin-protein transferase activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in Golgi membrane. Predicted to be part of VCP-NPL4-UFD1 AAA ATPase complex. Is expressed in 2-cell stage embryo and 4-cell stage embryo. Orthologous to human RNF125 (ring finger protein 125). [provided by Alliance of Genome Resources, Apr 2022]