Enables protein-disulfide reductase activity. Acts upstream of or within several processes, including cell redox homeostasis; peptidyl-proline hydroxylation to 4-hydroxy-L-proline; and protein maturation. Located in membrane. Orthologous to human ERO1B (endoplasmic reticulum oxidoreductase 1 beta). [provided by Alliance of Genome Resources, Apr 2022]