Peli1 - pellino 1

Enables ubiquitin protein ligase activity. Involved in negative regulation of necroptotic process. Acts upstream of or within several processes, including positive regulation of macromolecule metabolic process; positive regulation of signal transduction; and regulation of lymphocyte proliferation. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skin. Orthologous to human PELI1 (pellino E3 ubiquitin protein ligase 1). [provided by Alliance of Genome Resources, Apr 2022]