Smc6 - structural maintenance of chromosomes 6

Predicted to enable damaged DNA binding activity; single-stranded DNA binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in DNA recombination; cellular senescence; and positive regulation of chromosome segregation. Predicted to act upstream of or within DNA recombination and DNA repair. Located in chromosome; mitotic spindle pole; and nucleus. Part of Smc5-Smc6 complex. Is expressed in central nervous system; embryo; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human SMC6 (structural maintenance of chromosomes 6). [provided by Alliance of Genome Resources, Apr 2022]