Prpf18 - pre-mRNA processing factor 18

Predicted to be involved in generation of catalytic spliceosome for second transesterification step; negative regulation of cellular protein metabolic process; and nuclear retention of unspliced pre-mRNA at the site of transcription. Predicted to act upstream of or within mRNA processing. Predicted to be located in membrane. Predicted to be part of U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; genitourinary system; and sensory organ. Orthologous to human PRPF18 (pre-mRNA processing factor 18). [provided by Alliance of Genome Resources, Apr 2022]