Ndufa13 - NADH:ubiquinone oxidoreductase subunit A13

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Acts upstream of or within extrinsic apoptotic signaling pathway. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 28 and thyroid gland Hurthle cell carcinoma. Orthologous to several human genes including NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13). [provided by Alliance of Genome Resources, Apr 2022]