Smarca2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

Predicted to enable several functions, including chromatin binding activity; transcription cis-regulatory region binding activity; and transcription coactivator activity. Acts upstream of or within aortic smooth muscle cell differentiation; hematopoietic stem cell homeostasis; and negative regulation of cell population proliferation. Located in nucleus. Part of nBAF complex and npBAF complex. Is expressed in several structures, including cerebral cortex; early conceptus; genitourinary system; heart; and vitelline artery. Orthologous to human SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2). [provided by Alliance of Genome Resources, Apr 2022]