Fbxo5 - F-box protein 5

Predicted to enable anaphase-promoting complex binding activity; protein kinase binding activity; and ubiquitin ligase inhibitor activity. Involved in regulation of mitotic cell cycle. Acts upstream of or within several processes, including female gamete generation; microtubule polymerization; and negative regulation of meiotic nuclear division. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including brain ventricular layer; early conceptus; nephrogenic zone; oocyte; and rest of cerebellum marginal layer. Orthologous to human FBXO5 (F-box protein 5). [provided by Alliance of Genome Resources, Apr 2022]