Polr3k - polymerase (RNA) III (DNA directed) polypeptide K

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Predicted to contribute to DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in termination of RNA polymerase III transcription. Predicted to act upstream of or within defense response to virus and innate immune response. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Is expressed in several structures, including 1st branchial arch; alimentary system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human POLR3K (RNA polymerase III subunit K). [provided by Alliance of Genome Resources, Apr 2022]