Khdc3 - KH domain containing 3, subcortical maternal complex member

Predicted to enable RNA binding activity. Involved in several processes, including positive regulation of dendrite development; positive regulation of double-strand break repair via homologous recombination; and positive regulation of embryonic development. Acts upstream of or within mitotic spindle assembly; mitotic spindle assembly checkpoint signaling; and protein phosphorylation. Located in several cellular components, including apical cortex; centrosome; and mitochondrion. Part of subcortical maternal complex. Is expressed in cranial ganglion; dorsal root ganglion; early conceptus; ovary; and vibrissa. Human ortholog(s) of this gene implicated in gestational trophoblastic neoplasm. Orthologous to human KHDC3L (KH domain containing 3 like, subcortical maternal complex member). [provided by Alliance of Genome Resources, Apr 2022]