Shisa5 - shisa family member 5

Predicted to enable WW domain binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in endoplasmic reticulum and nuclear envelope. Is expressed in chorion; extraembryonic ectoderm; foregut diverticulum; and yolk sac. Orthologous to human SHISA5 (shisa family member 5). [provided by Alliance of Genome Resources, Apr 2022]