Wwp2 - WW domain containing E3 ubiquitin protein ligase 2

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and ubiquitin protein ligase activity. Involved in cellular protein metabolic process and regulation of transcription, DNA-templated. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including heart valve; respiratory system; sensory organ; skeleton; and tarsus. Orthologous to human WWP2 (WW domain containing E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Apr 2022]