Predicted to enable caspase binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to organic cyclic compound; negative regulation of intracellular signal transduction; and positive regulation of interferon-beta production. Predicted to act upstream of or within defense response to other organism; phosphorylation; and ribosome biogenesis. Predicted to be located in cytoplasm. Predicted to be part of preribosome, small subunit precursor. Predicted to be active in cytosol. Is expressed in ganglia; sensory organ; trigeminal nerve; and vibrissa. Orthologous to human RIOK3 (RIO kinase 3). [provided by Alliance of Genome Resources, Apr 2022]