Rnf186 - ring finger protein 186

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver and biliary system; and musculoskeletal system. Orthologous to human RNF186 (ring finger protein 186). [provided by Alliance of Genome Resources, Apr 2022]