Trim5 - tripartite motif-containing 5

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including defense response to other organism; positive regulation of NF-kappaB transcription factor activity; and regulation of signal transduction. Predicted to be located in P-body. Predicted to be active in cytosol and nucleoplasm. Predicted to colocalize with omegasome. Is expressed in adrenal gland; central nervous system; and retina. Orthologous to human TRIM5 (tripartite motif containing 5). [provided by Alliance of Genome Resources, Apr 2022]