Piezo2 - piezo-type mechanosensitive ion channel component 2

Enables mechanosensitive cation channel activity. Involved in detection of mechanical stimulus involved in sensory perception. Acts upstream of or within cation transport and regulation of membrane potential. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in dorsal root ganglion and lung. Human ortholog(s) of this gene implicated in distal arthrogryposis type 3 and distal arthrogryposis type 5. Orthologous to human PIEZO2 (piezo type mechanosensitive ion channel component 2). [provided by Alliance of Genome Resources, Apr 2022]