Myo3a - myosin IIIA

Enables actin filament binding activity; microfilament motor activity; and protein serine/threonine kinase activity. Involved in auditory receptor cell stereocilium organization; cochlea morphogenesis; and sensory perception of sound. Acts upstream of or within several processes, including positive regulation of filopodium assembly; protein phosphorylation; and regulation of actin filament length. Located in filopodium tip; photoreceptor inner segment; and stereocilium tip. Is expressed in cochlea and metanephros. Used to study autosomal recessive nonsyndromic deafness 30. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 30. Orthologous to human MYO3A (myosin IIIA). [provided by Alliance of Genome Resources, Apr 2022]