Thg1l - tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)

Predicted to enable several functions, including guanyl-nucleotide exchange factor activity; magnesium ion binding activity; and purine ribonucleoside triphosphate binding activity. Predicted to be involved in several processes, including protein homotetramerization; stress-induced mitochondrial fusion; and tRNA processing. Predicted to be located in mitochondrion. Predicted to be part of transferase complex. Human ortholog(s) of this gene implicated in autosomal recessive cerebellar ataxia. Orthologous to human THG1L (tRNA-histidine guanylyltransferase 1 like). [provided by Alliance of Genome Resources, Apr 2022]