Mthfd2l - methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

Predicted to enable methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in 10-formyltetrahydrofolate metabolic process and tetrahydrofolate interconversion. Predicted to act upstream of or within cellular amino acid biosynthetic process; one-carbon metabolic process; and purine nucleotide biosynthetic process. Predicted to be located in mitochondrial inner membrane and mitochondrial matrix. Predicted to be active in mitochondrion. Is expressed in several structures, including central nervous system; future brain; gonad; gut; and retina nuclear layer. Orthologous to human MTHFD2L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like). [provided by Alliance of Genome Resources, Apr 2022]