Skic8 - SKI8 subunit of superkiller complex

Predicted to be involved in several processes, including histone H3-K4 trimethylation; positive regulation of histone methylation; and transcription elongation from RNA polymerase II promoter. Predicted to act upstream of or within Wnt signaling pathway. Part of Cdc73/Paf1 complex. Is expressed in central nervous system; embryo; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human WDR61 (WD repeat domain 61). [provided by Alliance of Genome Resources, Apr 2022]