Kcnd3 - potassium voltage-gated channel subfamily D member 3
Alias:
Kv4.3
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
References Literature
Enables voltage-gated potassium channel activity. Contributes to A-type (transient outward) potassium channel activity. Involved in cellular response to BMP stimulus; potassium ion export across plasma membrane; and potassium ion import across plasma membrane. Located in several cellular components, including caveola; neuronal cell body; and perinuclear endoplasmic reticulum. Is integral component of plasma membrane. Part of voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to human KCND3 (potassium voltage-gated channel subfamily D member 3). [provided by Alliance of Genome Resources, Apr 2022]