Clpb - ClpB family mitochondrial disaggregase

Predicted to enable ATP hydrolysis activity. Predicted to be involved in RIG-I signaling pathway; antiviral innate immune response; and cellular response to heat. Predicted to be located in mitochondrial intermembrane space. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia. Orthologous to human CLPB (caseinolytic mitochondrial matrix peptidase chaperone subunit B). [provided by Alliance of Genome Resources, Apr 2022]