Bche - butyrylcholinesterase

Enables choline binding activity and cholinesterase activity. Involved in several processes, including neuroblast differentiation; response to folic acid; and response to glucocorticoid. Located in endoplasmic reticulum lumen; extracellular space; and membrane. Used to study amnestic disorder and hyperhomocysteinemia. Biomarker of leptospirosis and trypanosomiasis. Human ortholog(s) of this gene implicated in Alzheimer's disease; coronary artery disease (multiple); diabetes mellitus (multiple); epilepsy; and inherited metabolic disorder. Orthologous to human BCHE (butyrylcholinesterase). [provided by Alliance of Genome Resources, Apr 2022]