Suv39h2 - suppressor of variegation 3-9 2

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; chromatin binding activity; and histone-lysine N-methyltransferase activity. Involved in histone H3-K9 methylation; negative regulation of circadian rhythm; and negative regulation of transcription, DNA-templated. Acts upstream of or within histone H3-K9 methylation and male meiotic nuclear division. Located in heterochromatin and nucleus. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and limb. Orthologous to human SUV39H2 (SUV39H2 histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]