Bid - BH3 interacting domain death agonist

Predicted to enable ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of autophagy in response to ER overload; release of cytochrome c from mitochondria; and response to ischemia. Located in cytosol and mitochondrion. Used to study pre-malignant neoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist). [provided by Alliance of Genome Resources, Apr 2022]