Enables heparanase activity. Predicted to be involved in several processes, including heparan sulfate proteoglycan catabolic process; positive regulation of osteoblast proliferation; and positive regulation of protein kinase B signaling. Predicted to be located in lysosome; membrane raft; and nucleoplasm. Predicted to be part of heparanase complex. Predicted to be active in extracellular matrix and extracellular space. Orthologous to human HPSE (heparanase). [provided by Alliance of Genome Resources, Apr 2022]