Smn1 - survival of motor neuron 1, telomeric

Enables fibroblast growth factor binding activity. Involved in chemical synaptic transmission. Located in Gemini of coiled bodies; cytoplasm; and nucleolus. Human ortholog(s) of this gene implicated in Werdnig-Hoffmann disease; adult spinal muscular atrophy; intermediate spinal muscular atrophy; juvenile spinal muscular atrophy; and spinal muscular atrophy. Orthologous to several human genes including SMN2 (survival of motor neuron 2, centromeric). [provided by Alliance of Genome Resources, Apr 2022]