Predicted to enable oxysterol binding activity. Involved in cellular response to insulin stimulus; response to estradiol; and response to fatty acid. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Biomarker of fatty liver disease. Orthologous to human INSIG1 (insulin induced gene 1). [provided by Alliance of Genome Resources, Apr 2022]