Birc5 - baculoviral IAP repeat-containing 5

Predicted to enable several functions, including chaperone binding activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; and protein dimerization activity. Involved in several processes, including cellular response to ethanol; cellular response to stem cell factor stimulus; and response to glucocorticoid. Located in apical plasma membrane; cytoplasm; and nucleus. Used to study endometriosis and pulmonary hypertension. Biomarker of acute pancreatitis (multiple); artery disease (multiple); congestive heart failure; high grade glioma; and stomach carcinoma. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5). [provided by Alliance of Genome Resources, Apr 2022]