Sav1 - salvador family WW domain containing 1

Predicted to enable several functions, including identical protein binding activity; signaling receptor binding activity; and signaling receptor complex adaptor activity. Acts upstream of or within several processes, including epithelial cell differentiation; hippo signaling; and negative regulation of cell population proliferation. Predicted to be located in cytosol and nucleus. Predicted to be active in cell-cell junction; cytoplasm; and dendrite. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study colonic disease and hepatocellular carcinoma. Orthologous to human SAV1 (salvador family WW domain containing protein 1). [provided by Alliance of Genome Resources, Apr 2022]