Smc1a - structural maintenance of chromosomes 1A

Predicted to enable several functions, including chromatin binding activity; mediator complex binding activity; and protein heterodimerization activity. Involved in meiotic cell cycle. Predicted to be located in several cellular components, including kinetochore; mitotic spindle pole; and nuclear lumen. Predicted to be part of meiotic cohesin complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2 and developmental and epileptic encephalopathy. Orthologous to human SMC1A (structural maintenance of chromosomes 1A). [provided by Alliance of Genome Resources, Apr 2022]