Hsd17b10 - hydroxysteroid (17-beta) dehydrogenase 10

Enables several functions, including amyloid-beta binding activity; estrogen receptor binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in Leydig cell differentiation and cell aging. Located in mitochondrion. Human ortholog(s) of this gene implicated in chromosome Xp11.22 duplication syndrome; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10). [provided by Alliance of Genome Resources, Apr 2022]