Dact3 - dishevelled-binding antagonist of beta-catenin 3

Enables several functions, including delta-catenin binding activity; identical protein binding activity; and protein kinase C binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and negative regulation of epithelial to mesenchymal transition. Located in cytoplasm. Is expressed in several structures, including branchial arch artery; central nervous system; embryo mesenchyme; genitourinary system; and tooth. Orthologous to human DACT3 (dishevelled binding antagonist of beta catenin 3). [provided by Alliance of Genome Resources, Apr 2022]