Ppp2r2b - protein phosphatase 2, regulatory subunit B, beta

Predicted to enable protein phosphatase regulator activity. Involved in several processes, including mitochondrion organization; nervous system development; and positive regulation of neuron apoptotic process. Located in cytosol and mitochondrial outer membrane. Part of protein phosphatase type 2A complex. Colocalizes with cytoskeleton. Human ortholog(s) of this gene implicated in Alzheimer's disease; brain disease; breast cancer; and spinocerebellar ataxia type 12. Orthologous to human PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta). [provided by Alliance of Genome Resources, Apr 2022]