Slc18a3 - solute carrier family 18 member A3

Enables acetylcholine transmembrane transporter activity. Involved in acetylcholine transport and neurotransmitter loading into synaptic vesicle. Located in axon terminus and synaptic vesicle. Part of AP-1 adaptor complex and AP-2 adaptor complex. Is active in cholinergic synapse and neuromuscular junction. Is integral component of synaptic vesicle membrane. Biomarker of asthma and bladder disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 21. Orthologous to human SLC18A3 (solute carrier family 18 member A3). [provided by Alliance of Genome Resources, Apr 2022]