Twist2 - twist family bHLH transcription factor 2

Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in negative regulation of apoptotic process. Predicted to be located in cytoplasm; nucleolus; and nucleoplasm. Predicted to be part of transcription regulator complex. Human ortholog(s) of this gene implicated in Barber-Say syndrome; ablepharon macrostomia syndrome; and focal dermal hypoplasia. Orthologous to human TWIST2 (twist family bHLH transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]