Erbb4 - erb-b2 receptor tyrosine kinase 4

Predicted to enable several functions, including epidermal growth factor receptor binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including animal organ development; positive regulation of GABAergic synaptic transmission; and positive regulation of glucose import. Located in several cellular components, including caveola; postsynaptic density; and postsynaptic membrane. Colocalizes with inhibitory synapse. Used to study visual epilepsy. Biomarker of congestive heart failure; median neuropathy; radiculopathy; and schizophrenia. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4). [provided by Alliance of Genome Resources, Apr 2022]