Ambra1 - autophagy and beclin 1 regulator 1

Predicted to enable GTPase binding activity and ubiquitin protein ligase binding activity. Involved in cellular response to starvation; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of autophagy. Predicted to be located in axoneme; cytosol; and phagocytic vesicle. Predicted to be active in intracellular membrane-bounded organelle. Predicted to colocalize with mitochondrion. Orthologous to human AMBRA1 (autophagy and beclin 1 regulator 1). [provided by Alliance of Genome Resources, Apr 2022]