Erbin - Erbb2 interacting protein

Predicted to enable signaling receptor binding activity. Involved in negative regulation of monocyte chemotactic protein-1 production; negative regulation of nucleotide-binding activity oligomerization domain containing 2 signaling pathway; and regulation of postsynaptic membrane neurotransmitter receptor levels. Acts upstream of or within protein targeting. Located in basolateral plasma membrane and glutamatergic synapse. Is active in postsynapse. Is expressed in cerebral cortex and retina nuclear layer. Orthologous to human ERBIN (erbb2 interacting protein). [provided by Alliance of Genome Resources, Apr 2022]