Grk5 - G protein-coupled receptor kinase 5

Predicted to enable beta-adrenergic receptor kinase activity and protein serine/threonine kinase activity. Involved in negative regulation of G protein-coupled receptor signaling pathway; oligodendrocyte differentiation; and response to alkaloid. Predicted to be located in cytosol; nucleus; and plasma membrane. Predicted to be active in cytoplasm. Biomarker of Parkinson's disease and hypertension. Orthologous to human GRK5 (G protein-coupled receptor kinase 5). [provided by Alliance of Genome Resources, Apr 2022]